SenoBright* CESM can be used to confirm findings and localize lesions when screening results are inconclusive. It can be performed in less than 10 minutes – using the same mammography equipment, in the same room, with the same staff. Learn more about the benefits of SenoBright.

SenoBright is the first tool in the world to take advantage of contrast-enhanced spectral mammography (CESM), a technique based on dual-energy acquisitions. Using an iodinated contrast agent and low radiation dose, SenoBright can provide morphological images similar to standard digital mammograms and also contrast-enhanced images of abnormal vascular development around lesions. See more clinical images.

SenoBright CESM is available as an upgrade on Senographe* Essential, SenoCare* and Senographe DS* systems.


    Know more.

    SenoBright CESM gives you more information to help you get the answers you need when faced with inconclusive mammogram and ultrasound findings. SenoBright highlights unusual blood flow that may be cause for suspicion, with both a low energy image showing tissue density and a contrast-enhanced image with the background signal subtracted out.

    “We’ve had a great experience with CESM. It’s really become just one more tool in our toolbox. Sometimes the answers are just not there and you don’t really have a warm and fuzzy feeling that you have gotten to the conclusion, especially if the woman has dense tissue and you know that something might be hiding if they are high risk […]” 

    - Dr. Shroeder Radiologist, and Medical Director, Eastern Radiologists Inc., North Carolina

    With CESM, whether providing information to a breast surgeon, referring physician, or oncologist, they'll see the same mammographic views they're used to seeing.

    Easy access. 

    A SenoBright CESM is much like a regular mammography exam and can be performed in less than ten minutes. It is not restrictive for patients who may have difficulty accessing other diagnostic tests for any variety of reasons, such as financial limitations, claustrophobia, weight, delays associated with access, etc. Link to how an exam is performed. See how a CESM exam is performed

    "When there are doubts, which are common in breast oncology and breast imaging, you can provide [patients] with a tool that is available on-site […] and that allows them to have the results after 30 minutes."

    - Dr. Suzette Delaloge, Head of the Breast Cancer Group at the Institut Gustave Roussy, Paris, France

    Follow up faster.

    With SenoBright, you can perform additional tests right away without changing rooms or equipment – allowing you to follow up faster. It is much like a regular mammography exam and can be performed in less than ten minutes.

    Providing answers sooner can help minimize the anxiety of a concerned patient waiting for results. Learn more about how faster follow-up can reduce patient anxiety.

    "CESM has been a really helpful tool in shortening the [breast cancer diagnosis] cycle from initial diagnosis to definitive surgical treatment."

    - Dr. Bruce Schroeder, Radiologist and Medical Director Eastern Radiologists Inc., North Carolina

    Optimize your review. 

    GE's MammoWorkstation is a powerful reading tool specifically designed to work with advanced applications, such as SenoBright. The workstation’s customized hanging protocols let each radiologist arrange images according to personal preference for exceptional reading efficiency — and see them the same, consistent way at every login. Learn more about the MammoWorkstation.


    CESM Technology

    Contrast-Enhanced Mammography 

    Contrast-enhanced mammography depicts areas in the breast associated with hypervascularized breast lesions, after an iodinated contrast agent has been injected.

    Conventional mammography energy levels are only slightly sensitive to the presence of iodine in the breast. As demonstrated in Figure 1a, atypical clinical concentration of iodine in the breast results in a low signal intensity, and is hardly distinguishable from the background breast morphology. To obtain images that efficiently highlight iodine, cancellation of the background breast tissue has been proposed.

    One option to cancel the background breast tissue and spotlight iodine enhanced areas is Contrast Enhanced Spectral Mammography (CESM), a technique based on dual-energy acquisitions, where two images are acquired using distinct low-energy (LE – standard mammography KV and filtration) and high-energy (HE – higher KV with strong filtration) X-ray spectra (Figure 1a and 1b). The differences between X-ray attenuation of iodine and breast tissues at these two energy levels are exploited to suppress the background breast tissue (Figure 1c).

    Figure 1. Illustration of CESM principle on a breast tissue equivalent structured phantom containing disks with typical clinical iodine concentrations. (a) The low energy image isacquired using standard mammography energy levels. Note that the iodine is difficult to detect. (b) The high energy image is acquired using a mean energy above the K edge ofiodine. Iodine detectability is improved but still limited by the structured tissue equivalent background. Breast tissue contrast is also deteriorated at these high energy levels. (c)In the iodine image, the background tissue is suppressed and the iodine is easily visualized. (The radio-lucent specks are artifacts in the phantom).

    View Cases

    Case #1

    Case #2

    Case #3

    Case #4





    Physician Testimonials

    “SenoBright has filled our single biggest void: how to handle an inconclusive mammogram and ultrasound expeditiously and in-house.” 

    - Dr. Funk, Surgical Breast Specialist and Founder, Pink Lotus Breast Center, CA, USA

    “We’ve had a great experience with CESM. It’s really become just one more tool in our toolbox. We have had some referring clinicians who […] send us many patients because they’ve come to love it and they’ve come to trust it. Patients then come back to them and say ‘that was easy’.” 

    - Dr. Bruce Shroeder, Radiologist and Medical Director, Eastern Radiologists Inc., North Carolina

    “When there are doubts [...] you can provide [patients] with a tool that is available on-site, that can be performed in less than 10 minutes, and that allows them to have the results after 30 minutes.” 

    - Dr. Delaloge, Oncologist, Institut Gustave Roussy (IGR), Villejuif, France                           

    “CESM helps to increase detection for early breast cancer in conjunction with other tests. The results can be given to patients before they leave the clinic so it is very helpful to manage patients’ anxiety.” 

    - Dr. Liao, Radiologist, Cooper Breast Imaging Centers, NJ, USA

    SenoBright Exam

    SenoBright exam

    One injection.
    One complete bi-lateral exam.
    Four views.

    Easy to integrate into your practice

    SenoBright has been designed to provide a workflow for streamlined clinical use and a comfortable exam experience for the patient.

    A SenoBright exam can be performed on mammography equipment immediately following a standard mammogram and/or ultrasound. The exam is very similar to a standard mammography exam, with the exception of the intravenous injection, which is administered exactly like injections for CT exams. The exam designed to take less than 10 minutes. After an initial 2 minute wait following the injection, SenoBright performs the 4 standard views (high and low energy images) in 5 minutes (see figure 1).

    The system automatically acquires the spectral data necessary to automatically create two images per view. Rapid image acquisition has been made possible by alternating quickly between the LE and HE X-ray spectra, thanks to rapid switching between the X-ray tube voltages and filters and a fast detector read-out.

    Figure 1 illustrates a typical exam with SenoBright. First, an iodinated contrast agent is injected intravenously while the patient is either comfortably seated or lying down and with the breast uncompressed for patient comfort. Typically two minutes after start of injection, the breast is positioned and compressed for the first view, and the first image pair is acquired. After image acquisition, the breast is automatically decompressed. Next, three more image pairs can be acquired in a similar way, to achieve a complete bilateral two-view exam. In this example, the total image acquisition time lasts about 5 minutes and the total procedure lasts about 7 minutes. The ease of use and short exam time add up to an efficient workflow aimed at a comfortable experience for the patient.


    See how a CESM is performed.                                       "It was surprising that this was so easy." Earline W., breast cancer patient